What is HPV? One article will help you understand

　　HPV, the human papillomavirus, has attracted much attention in recent years. It is related to various disease related, especially cervical cancer . So, what exactly is HPV? The following is a detailed introduction for you.

What is HPV

　　definition: Human papillomavirus (HPV) is a double-stranded circular DNA virus that can cause skin Squamous epithelial proliferation of mucous membranes.

　　Transmission route: Mainly through sexually transmitted infections, it can also be transmitted through indirect contact, such as sharing towels, toilet seats, etc.

HPV typing

　　High-risk HPV: Persistent infection with high-risk HPV may lead to malignant tumors such as cervical cancer and anal cancer. Common high-risk types include HPV16, 18, etc.

　　Low-risk HPV: Low-risk HPV usually causes benign sexually transmitted diseases Changes, such as genital warts. Common low-risk types include HPV6, 11, etc.

carcinogenesis mechanism

　　E6/E7 gene: The E6/E7 genes of high-risk HPV can inactivate tumor suppressor genes, leading to abnormal cell proliferation and canceration.

　　persistent infection: Only persistent infection with high-risk HPV increases the risk of cancer. Most HPV infections can be cleared by autoimmunity.

HPV test

　　Detection method: Common detection methods include nucleic acid detection, mRNA detection, etc., which can be used for typing detection to determine the HPV subtype of infection.

　　screening strategy: Recommended for those who have sex female Regular HPV testing and TCT examinations, combined screening can increase the detection rate.

HPV vaccine

　　Vaccine type: Currently, there are bivalent, quadrivalent and nine-valent HPV vaccines, which can prevent HPV infection of corresponding subtypes.

　　Vaccination age: The vaccination ages for different vaccines vary, and it is generally recommended to vaccinate as early as possible.

　　Vaccination contraindications: People who are allergic to vaccine components or are in the acute stage of fever or disease should not be vaccinated.

　　Human papillomavirus (HPV) is a common sexually transmitted infection with multiple subtypes. Persistent infection with high-risk HPV may cause cervical cancer, while low-risk HPV may cause genital warts. HPV testing and vaccination are important means of preventing related diseases.