There are contraindications for birth control pills and these people cannot take them.

　　What are the contraindications for oral contraceptives?

　　1. Take together with antibiotics

　　Someone once observed 38 women who took birth control pills and used ampicillin, neomycin, tetracycline, trimethoprim-sulfamethoxazole, and chloramphenicol at the same time, resulting in contraceptive failure. It was found that the reason for the failure was that the antibiotics inhibited the intestinal bacteria, causing them to produce Grape The amount of uronidase is greatly reduced, which affects the absorption of contraceptive pills in the intestines, causing the concentration of contraceptive pills in the blood to decrease and failing to achieve the contraceptive effect.

　　2. Take it together with rifampicin

　　It is a commonly used anti-tuberculosis drug. It can accelerate the metabolism of norethindrone and ethinyl estradiol, the main components of oral contraceptives, reduce the drug concentration in the blood, and may also cause Uterus Part of the endometrium may fall off, causing spotting or dripping, and at the same time, the efficacy of the contraceptive pill may be reduced, resulting in contraceptive failure.

　　3. Resistance epilepsy Take medicine together

　　This type of drug is an enzyme inducer, such as phenobarbital, phenytoin, carbamazepine, epilepticone, etc. When women with epilepsy take such drugs, they can increase the amount of drug-metabolizing enzymes in liver cells, accelerating the destruction of the efficacy of oral contraceptives, and also increase the binding rate of progesterone to globulin, greatly reducing the concentration of free progesterone, leading to contraceptive ineffectiveness.

　　4. Take it together with enzyme accelerator

　　For example, sedatives and sleeping pills such as metoprolol, and drugs for treating rheumatoid arthritis such as phenylbutazone. These drugs have enzymatic effects, which can promote the metabolic activity of drugs catalyzed by liver mitochondrial enzymes, accelerate the metabolism of oral contraceptives, and reduce the contraceptive effect. If sleeping pills must be used, diazepam can be used instead. Do not take other sedative and sleeping pills.

　　5. Take together with griseofulvin

　　This is an antifungal drug. When used together with contraceptive pills, it can change the activity of liver granulase, causing the concentration of steroid hormones to decrease, resulting in decreased menstrual blood, leading to contraceptive failure. It has been reported abroad that among more than 20 women taking birth control pills, 15 had reduced menstrual blood volume and 5 had menstrual bleeding after taking griseofulvin. amenorrhea , 2 are pregnant.

　　Eight categories of contraceptive pills that should not be taken female：

　　1. Breastfeeding women

　　Reduce the amount of milk produced, and estrogen can also enter through the milk baby In the body, it can cause breast enlargement, uterine bleeding, etc. Therefore, lactating women should not take birth control pills.

　　2. Women with epilepsy

　　Reduce its contraceptive effect. Women with epilepsy should not take contraceptive pills during treatment.

　　3. Obese women over 40 years old

　　Long-term use of contraceptive pills may cause hyperlipidemia or cardiovascular and cerebrovascular disease in these women disease。

　　4. Women with low menstrual flow

　　It can reduce menstrual flow and even cause amenorrhea. Therefore, women with low menstrual flow should not take birth control pills.

　　5. Women with smoking habits

　　If women with smoking habits take birth control pills, the incidence and mortality of myocardial infarction are about 10 times higher than those of women who do not smoke.

　　6. Women with acute or chronic hepatitis or nephritis

　　If people with poor liver and kidney function take birth control pills, it will easily cause the accumulation of drugs in the body, increase the burden on their liver and kidneys, and worsen the condition.

　　7. Women with cardiac insufficiency

　　It causes electrolyte imbalance in the body of the person taking the medicine, thereby increasing the burden on the heart of the person taking the medicine. Therefore, women with cardiac insufficiency should not take birth control pills.

　　8. Women with thromboembolic disease

　　Induce the formation of thrombosis. Therefore, women with thromboembolic diseases such as cerebral thrombosis, myocardial infarction or vasculitis should not take birth control pills.