Commonly used syphilis treatment for bone and joint syphilis

　　Early stage syphilis can produce bone and joint lesions

　　Treponema pallidum in pregnant women with syphilis invades the placenta and invades through the umbilical cord vein fetus Those who become ill later are congenital syphilis. This type of syphilis can produce bone and joint lesions in its early stages. Acquired syphilis is caused by Treponema pallidum skin Or mucosal contact, invasion from cracks and damaged parts and causing disease, a few spread through blood transfusion.

　　After the diagnosis is confirmed, treatment should be carried out as soon as possible. Couples of syphilis patients and parents of pediatric patients are required to receive treatment at the same time. A general physical examination should be performed before treatment. The treatment principle for bone and joint syphilis is a combination of systemic therapy and local therapy, but systemic therapy is the mainstay.

　　Commonly used treatments to dispel plum blossoms:

　　1. Arsenic and bismuth combination therapy　

　　For use in patients allergic to penicillin. In the treatment of plum blossom dispelling therapy, attention should also be paid to local symptomatic treatment. If affected, the affected limb should be immobilized. Use a cast or external fixator to keep the affected limb in a functional position. Clean and change the dressing or remove the lesions of ulcer wounds in a timely manner. For patients with long-tube bone periostitis who have severe pain, fenestration decompression surgery can significantly reduce pain. However, it is more difficult to treat some deformities and Charcot joints.

　　2. Oil penicillin therapy　

　　For patients suffering from congenital syphilis, under two years old, the total dose of 350,000 units per kilogram of body weight is calculated as a course of treatment, divided into 10 intramuscular injections, once a day or every other day. For those aged below 14 to 2 years old, the calculation is based on 250,000 units per kilogram of body weight. Generally, the total amount of a course of treatment does not exceed 6 million units. A total of two courses of treatment were given, with an interval of two weeks.

　　For adults with secondary and late-stage syphilis, 6 million units are used as a course of treatment, and 600,000 units are injected daily. For recurrent syphilis, the total dose for one course of treatment is 12 million units. Inject 600,000 units daily for 20 days.

　　Syphilis is an infectious disease mainly caused by sexual contact and can be prevented.

　　From a long-term perspective, it is crucial to vigorously carry out publicity on the causes of syphilis and the harm of the disease to the human body, try to improve people's cultural level and moral concepts, and strengthen legal supervision. At the same time, establish sexually transmitted diseases The prevention and treatment network enables syphilis patients to receive early diagnosis and receive timely and correct treatment.