Causes and dangers of genital warts

　　What are the causes and dangers of genital warts? Do you know the causes and dangers of genital warts? Do you understand the causes and dangers of genital warts? HPV is present in skin It causes warts and proliferative lesions on the pharynx, perianal, and genital mucosa. The virus type is a small DNA virus. Most of the lesions caused by HPV infection are benign and can resolve on their own, but there are also cases of worsening. For example, there are reports of squamous cell carcinoma forming on the perianal and genital mucosa. There are also rare hereditary skin diseases, skin cancer secondary to epidermodysplasia verruciformis (EV), etc., in which HPV has been detected in cancer cells.

　　HPV is a member of genus A of the family Papovaviridae. The virus particle has a diameter of 50-55 nm and is composed of a regular icosahedral virus without a membrane. It consists of a circular double-stranded DNA of 7900 base pairs. The size and shape of the virus particles under an electron microscope are very similar to oral polyomavirus. Papillomavirus (PV) is species-specific, and HPV has not been propagated in tissue culture or experimental animal models.

　　Structural protein composition of the virus: 85% of the PV particles. Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) can determine that the virus has a major capsid protein with a molecular weight of 56.000; a minor capsid protein with a molecular weight of 76.000. Four cellular histones were found to be related to the viral DNA.

　　The genome structures of all HPV viruses are similar. The types and subtypes of the virus can be determined based on DNA hybridization procedures under strict conditions. Only 50% of the DNA of different HPV types cross-hybridizes with other types of viral DNA. So far, more than 60 HPV types have been discovered. As research deepens, more new HPV types will be identified.