6 medicines that make birth control pills ineffective
Rifampicin: It can accelerate the metabolism of norethindrone and ethinyl estradiol, the main components of oral contraceptives, reduce the drug concentration in the blood, and may also cause Uterus Part of the endometrium falls off, causing spotting or bleeding, and at the same time, the efficacy of contraceptive drugs is reduced, resulting in contraceptive failure.
Antibiotics: Someone once treated 38 women with ampicillin, neomycin, cotrimoxazole, chloramphenicol, and furanthamidine when taking birth control pills. female Observations were made and it was found that the reason for their pregnancy was that antibiotics inhibited the intestinal bacteria and caused the production of Grape The amount of uronidase is greatly reduced, which affects the absorption of contraceptives in the large intestine and reduces the concentration of contraceptives in the blood.
anti- epilepsy medicine: This type of drugs is enzyme inducers, such as phenobarbital, phenytoin, carbamazepine, epilepticone, etc. When women with epilepsy take such drugs, they can increase the amount of drug-metabolizing enzymes in liver cells, accelerating the destruction of oral contraceptives, and also increase the binding rate of progesterone and globulin, greatly reducing the concentration of free drugs, leading to contraceptive failure.
griseofulvin : It is an antifungal drug. When used together with contraceptives, it can change the activity of liver microsomal enzymes, reduce steroid hormones, reduce menstrual blood, and lead to contraceptive failure.
Enzyme accelerator : For example, sedatives and sleeping pills such as meperidone, phenylbutazone and other drugs for treating rheumatoid arthritis, these drugs have enzymatic effects and can promote the metabolic activity of liver microsomal enzymes to catalyze drugs, accelerate the metabolism of oral contraceptives, and reduce the contraceptive effect. If sleeping pills must be used, diazepam can be used instead.
hormone: Such as prednisone, dexamethasone, etc., which increase when taking contraceptive pills at the same time skin Although it has the function of hormones, it can also delay the metabolism of corticosteroids and greatly increase its side effects. 》》》 You can eat these foods if you have body pain
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