The latest treatment methods for genital warts

　　Genital warts (condyloma acuminatum, CA) are caused by the human papilloma virus. They often occur in the anus and external genitalia and are mainly transmitted through sexual intercourse. Genital warts are one of the most common STDs worldwide, with the incidence rate abroad accounting for sexually transmitted diseases ranked second, and there is still an increasing trend; the reported incidence rate in China in 2002 was 12.94/100,000.

　　Etiology and pathogenesis: Humans are the only host of human papillomavirus (HPV). Currently, HPV is divided into more than 100 subtypes using molecular biology techniques. The viruses that cause genital warts are mainly HPV-6, -11, -16, -18 and other types. HPV mainly infects epithelial tissues. Recently, a large amount of literature and basic clinical Research has fully confirmed the causative role of HPV in the occurrence of anogenital cancer. HPV-16, -18, -45, and -56 types are the most common causative agents. cervical cancer High risk type.

　　Clinical manifestations: This disease usually occurs in sexually active young and middle-aged people. The incubation period is generally 1 to 8 months, with an average of 3 months. External genitalia and around the anus skin The moist areas of the mucous membrane are the most common areas. male It is more common in the glans, coronal sulcus, foreskin frenulum, urethral opening, penis, and perineum. It is more common in the anus and rectum in homosexuals. female It is more common in the labia majora, vaginal opening, clitoris, vagina, cervix, perineum and perianal area; in a few patients, it can be found in parts other than the anogenital area (such as mouth, armpits, breasts, between toes, etc.). The skin lesions initially appear as single or multiple scattered light red papules with soft texture and sharp tips, which gradually increase in size. According to the shape of the warts, they can be divided into sessile type (that is, papule-like skin lesions) and stalked type. The latter can be papillary, cauliflower-shaped, comb-shaped, and The warts are mushroom-like; the warts are often white, pink or gray, and the surface is prone to erosion, exudation, maceration and ulceration, and may be complicated by bleeding and infection. Most patients have no obvious symptoms, and a few may experience foreign body sensation, burning, itching or discomfort during sexual intercourse. Warts on the cervix are usually small, with clear boundaries and smooth or granular or grooved surfaces. They can increase in size significantly during pregnancy. A small number of patients have excessive wart proliferation and become giant genital warts (Buschke-loewenstein tumors), which are often related to HPV-6 infection, and some may undergo malignant transformation.

　　At present, the treatment of genital warts mainly uses oral antiviral drugs, interferon, laser and other methods, among which interferon treatment is the most commonly used method. These drugs mainly control the development of the disease by inhibiting the replication of the virus, but they cannot completely kill and eliminate the virus. If the drugs are stopped, relapse will occur; long-term use of drugs will lead to the development of drug resistance, making subsequent treatment more difficult.

　　my country part Hospital The latest international treatment high-tech project 863 high-end technology biological therapy is used to treat genital warts, which has been recognized and clinically verified by national authoritative departments. Mechanism of action: Take the patient's own infected warts or infected exfoliated cells, and use genetic and immune engineering methods to artificially intervene to produce antibodies. This immune serum protein antibody with the ability to kill viruses is extracted and injected into the patient after sterilization. The immune protein antibody itself is extracted from the patient's own infected tissue and is consistent with the patient's own chromosomes and DNA. It avoids rejection reactions and directly activates itself to form this virus-clearing antibody, achieving the goal of complete and complete cure. The cure rate has reached 100%.